Author

E. Nevarez-Munoz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

B. S. Magenheimer· 2 shared R. L. Maser· 2 shared S. Pawnikar· 2 shared Y. Miao· 2 shared A. Haldane· 1 shared K. Joshi· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersBiochemistry

B. S. Magenheimer

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2 papers

Recent·Most cited

Activation of Polycystin-1 Signaling by Binding of Stalk-derived Peptide Agonists

S. Pawnikar, B. S. Magenheimer, K. Joshi, E. Nevarez-Munoz, A. Haldane, R. L. Maser, Y. Miao

This study identifies stalk-derived peptides that activate PC1 signaling by binding to specific regions, revealing structural dynamics and potential therapeutic applications for ADPKD.

bioRxiv · Jan 6, 2024Biochemistry

Mechanism of Tethered Agonist-Mediated Signaling by Polycystin-1

S. Pawnikar, B. S. Magenheimer, E. Nevarez-Munoz, R. L. Maser, Y. Miao

This paper investigates the mechanism of tethered agonist-mediated signaling in PC1 CTF using simulations and experiments, revealing an allosteric pathway involving specific residue interactions.

bioRxiv · Aug 5, 2021Biochemistry