Overexpression of HLA class I predominantly on alpha cell in at risk individuals for type 1 diabetes
M. A. Benkahla, S. Sabouri, W. B. Kiosses, S. Rajendran, E. Quesada-Masachs, M. G. von Herrath
This study shows HLA-I hyper-expression occurs in islets of autoantibody-positive donors before T1D diagnosis and is predominantly on alpha cells.
bioRxiv · Jul 13, 2020Immunology