Point mutations in Arf1 reveal cooperative effects of the N-terminal region and myristate for GTPase-activating protein catalytic activity
E. Rosenberg, X. Jian, O. Soubias, R. Jackson, E. Gladu, E. Andersen, L. Esser, A. Sodt, D. Xia, R. A. Byrd, P. A. Randazzo
The paper investigates how point mutations in Arf1 affect its interaction with GAPs, revealing cooperative effects between the N-terminal region and myristate on catalytic activity.
bioRxiv · Nov 15, 2023 · PreprintBiochemistry