Author

E. Spinetti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 1

Frequent Co-Authors

G. E. Karagoz· 2 shared R. Covino· 2 shared A. Muratovic· 1 shared A. S. Anisimova· 1 shared B. R. Burgeois· 1 shared G. A. Versteeg· 1 shared H. Hornegger· 1 shared I. Fischer· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

G. E. Karagoz

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2 papers

Recent·Most cited

IGF2BP1 phosphorylation regulates ribonucleoprotein condensate formation by impairing low-affinity protein and RNA interactions

H. Hornegger, A. Muratovic, A. S. Anisimova, B. R. Burgeois, E. Spinetti, R. Covino, T. Madl, G. E. Karagoz

This study shows that phosphorylation of IGF2BP1 at S181 and Y396 modulates RNP condensate formation by altering low-affinity interactions with RNA and protein partners.

bioRxiv · Dec 5, 2023 · PreprintBiochemistry

Stress-induced clustering of the UPR sensor IRE1 is driven by disordered regions within its ER lumenal domain

P. Kettel, L. Marosits, E. Spinetti, M. Rechberger, P. Radler, I. Niedermoser, I. Fischer, G. A. Versteeg, M. Loose, R. Covino, G. E. Karagoz

This study shows that IRE1's ER lumenal domain forms dynamic condensates stabilized by membranes and unfolded polypeptides, which are essential for its clustering and signaling.

bioRxiv · Mar 30, 2023 · PreprintCell Biology