Author

T. Madl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3 Microbiology· 3 Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 7 Organism:human· 7 Research Focus:cell signaling & trafficking· 4 Research Focus:cell type annotation· 4 Research Focus:differential expression· 3 Research Focus:metabolism & bioenergetics· 3 Assay:metabolomics· 3 Assay:proteomics· 3

Frequent Co-Authors

C. Moissl-Eichinger· 3 shared H. Habisch· 2 shared R. Malli· 2 shared A. Farzi· 1 shared A. J. Deutsch· 1 shared A. J. Heck· 1 shared A. Mahnert· 1 shared A. Muratovic· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

C. Moissl-Eichinger

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

IGF2BP1 phosphorylation regulates ribonucleoprotein condensate formation by impairing low-affinity protein and RNA interactions

H. Hornegger, A. Muratovic, A. S. Anisimova, B. R. Burgeois, E. Spinetti, R. Covino, T. Madl, G. E. Karagoz

This study shows that phosphorylation of IGF2BP1 at S181 and Y396 modulates RNP condensate formation by altering low-affinity interactions with RNA and protein partners.

bioRxiv · Dec 5, 2023 · PreprintBiochemistry

Fecal microbiota transplantation from individual with bipolar disorder and healthy control elicits distinct behaviors and metabolite profiles in mice

G. Bukowski-Thall, F. Fellendorf, S. Gorkiewicz, K. C. K. Ip, L. Schmidt, M. Durdevic, H. Habisch, S. Mörkl, J. Wagner-Skacel, S. Bengesser, M. Lenger, N. Dalkner, G. Gorkiewicz, C. Högenauer, T. Madl, , E. Reininghaus

This study uses FMT from BD and healthy donors to show distinct behavioral and metabolite profiles in mice, implicating gut-brain signaling in BD.

bioRxiv · Nov 16, 2023 · PreprintMicrobiology

Hexokinase 1 forms rings that constrict mitochondria during energy stress

J. Pilic, B. Gottschalk, B. Bourgeois, H. Habisch, Z. Koshenov, F. E. Oflaz, Y. C. Erdogan, V. Shoshan-Barmatz, T. Madl, W. F. Graier, R. Malli

This study identifies that hexokinase 1 forms rings around mitochondria during energy stress, constraining mitochondria and rewiring metabolism by displacing Drp1.

bioRxiv · Mar 20, 2023 · PreprintCell Biology

Acinar-to-ductal metaplasia in the pancreas requires a glycolytic switch and functional mitochondria

T. Neuss, N. Wirges, M.-C. Chen, S. Usluer, R. Oellinger, S. Lier, M. Dudek, T. Madl, M. Jastroch, K. Steiger, W. Schmitz, H. Einwaechter, R. M. Schmid

This study identifies a glycolytic switch and functional mitochondria as essential for acinar-to-ductal metaplasia, a key step in pancreatic carcinogenesis.

bioRxiv · Jun 27, 2022 · PreprintCancer Biology

Fasting reverses drug-resistance in hepatocellular carcinoma through p53-dependent metabolic synergism

J. Krstic, I. Reinisch, K. Schindlmaier, M. Galhuber, N. Berger, N. Kupper, E. Moyschewitz, M. Auer, H. Michenthaler, C. Noessing, M. R. Depaoli, J. Ramadani-Muja, S. Stryeck, M. Pichler, B. Rinner, , A. Prokesch

This study shows that fasting enhances the effectiveness of sorafenib in hepatocellular carcinoma by reversing drug resistance through p53-dependent metabolic changes.

bioRxiv · Feb 10, 2021Cancer Biology

Methane emission of humans is explained by dietary habits, host genetics, local formate availability and a uniform archaeome

C. Kumpitsch, F. Fischmeister, A. Mahnert, S. Lackner, M. Wilding, C. Sturm, A. Springer, T. Madl, S. Holasek, C. Hoegenauer, I. Berg, V. Schoepf, C. Moissl-Eichinger

The paper identifies factors explaining human methane emission, including diet, genetics, formate availability, and microbiome composition.

bioRxiv · Dec 21, 2020 · PreprintMicrobiology

N-acetylaspartate improves cell survival when glucose is limiting

H. F. Alkan, K. E. Walter, H. Hackl, M. Vander Heiden, T. Madl, J. Bogner-Strauss

The paper shows N-acetylaspartate (NAA) supports cell survival in low-glucose conditions by maintaining UDP-GlcNAc levels and reducing ER stress, independent of its breakdown into aspartate or acetate.

bioRxiv · May 28, 2020 · PreprintCancer Biology

Human Milk Oligosaccharides modulate the risk for preterm birth in a microbiome dependent and independent manner

M.-R. Pausan, V. Kolovetsiou-Kreiner, G. L. Richter, T. Madl, E. Giselbrecht, E.-C. Weiss, E. Jantscher-Krenn, C. Moissl-Eichinger

The paper investigates how human milk oligosaccharides (HMOs) in blood and urine affect the risk of preterm birth through microbiome-dependent and independent mechanisms.

bioRxiv · Jun 27, 2019Microbiology

Cysteine oxidation triggers amyloid fibril formation of the tumor suppressor p16INK4A

C. Goebl, V. Morris, L. van Dam, M. Visscher, P. Polderman, C. Hartlmueller, H. de Ruiter, M. Hora, L. Liesinger, R. Birner-Gruenberger, H. Vos, B. Reif, T. Madl, T. Dansen

This study shows that cysteine oxidation in p16INK4A leads to amyloid fibril formation, which inactivates its tumor suppressor function.

bioRxiv · Jan 2, 2019Biochemistry