Reactive oxygen species prevent lysosome coalescence during PIKfyve inhibition
G. T. Saffi, E. Tang, S. Inpanathan, S. Mamand, A. Fountain, L. Salmena, R. J. Botelho
This study shows that reactive oxygen species (ROS) prevent lysosome coalescence during PIKfyve inhibition through distinct mechanisms depending on the ROS type.
bioRxiv · Jun 17, 2021Cell Biology