Deficits in Behavioral and Neuronal Pattern Separation in Temporal Lobe Epilepsy
A.D. Madar, J.A. Pfammatter, J. Bordenave, E.I. Plumley, S. Ravi, M. Cowie, E.P. Wallace, B.P. Hermann, R.K. Maganti, M.V. Jones
This study shows that temporal lobe epilepsy leads to deficits in pattern separation in the dentate gyrus, causing mnemonic discrimination impairments in both humans and mice.
Journal of Neuroscience · Oct 7, 2021Peer-reviewedNeuroscience