Design of readers for pathological PTM proteoforms in Alzheimer's disease
Kejia Wu, Tiana Schantz, Lemuel Chang, Prarthna Chabria, Elaina Bashaw, Thejesh Reddy Kalatturu, Doo Yeon Kim, An‐Qi Chen, Nathaniel Corley, Asim K. Bera, Alex Kang, Hannah Nguyen, Johnny Mendoza, Xinting Li, Magnus S. Bauer, , David A. Baker
The paper designs and validates protein readers that specifically detect disease-related modifications in Tau and Abeta in Alzheimer's disease models and human samples.
bioRxiv · Oct 21, 2026 · PreprintBioengineering