Efficient murine cardiac phenotyping by combining synchrotron-based phase-contrast micro-CT, histology, immunofluorescence and spatial transcriptomics
Niccolò Peruzzi, Ayse Ceren Mutgan, Kinga I. Gawlik, Timothy J. Mead, Tuva Jerlhagen Forsgren, Elin Lagervall, Till Dreier, Robin Krüger, Elna Lampei, Jenny Romell, Rapolas Spalinskas, Madeleine Durbeej, Suneel Apte, Martin Bech, Anne Bonnin, , Karin Tran‐Lundmark
The paper combines SRPC-microCT with spatial transcriptomics and histology to enable 3D cardiac phenotyping in mice, linking structural and molecular data.
bioRxiv · Apr 28, 2026 · PreprintDevelopmental Biology