The Cornea Harbors a Tricellular Neuro-Immune Niche that Underpins Touch Sensation
Sejiro Littleton, EM Jacob, Yu Chen, Emily G. O’Koren, Nancy Suyapa Reyes, R Matthew, Joan Kalnitsky, Seitaro Komai, Allison M. Nguyen-Thai, Sachin Parikh, W Perez, S Mitra, J Neff, Florent Ginhoux, Victor L. Perez, , Daniel R. Saban
The paper identifies a tricellular niche in the cornea involving macrophages, nerves, and Schwann cells that supports Piezo2-mediated touch sensation.
bioRxiv · Jul 28, 2025 · PreprintImmunology