In Vivo Rescue of Cardiomyopathy Through Cardiac Prime Editing
Wenjing Liang, Lindsey M. Rollosson, Emilee Easter, Huanyu Zhou, Cristina Dee-Hoskins, Amara Greer-Short, Timothy C. Hoey, Laura Marie Lombardi, Kathryn N. Ivey, Ze Cheng
This study demonstrates the use of in vivo prime editing to correct a cardiomyopathy-causing mutation in a humanized mouse model, rescuing disease phenotypes.
bioRxiv · Apr 20, 2026 · PreprintBioengineering