Macrophage calcium signaling dynamics revealed using genetically-encoded sensors
Silke Blair Chalmers, Teneale A. Stewart, Katherine Hughes, Anie Kurumlian, Mathilde Folacci, Krystyna A. Gieniec, Alexander J. Stevenson, Ngari Teakle, Anuj Sehgal, Emma Paydari, Jesper Skovhus Thomsen, Katharine M. Irvine, Elvis Pandžić, Kate Poole, David Arthur Hume, Felicity M. Davis
This study uses genetic biosensors to visualize calcium signaling dynamics in macrophages, revealing mechanosensitivity and the effects of Piezo1 channel ablation.
bioRxiv · Oct 28, 2026 · PreprintImmunology