Enhanced glymphatic CSF tracer influx during α2-adrenergic agonist anesthesia is independent of tracer injection duration
Tianyi Tong, Evan J. Newbold, Jiayi Wang, Emma Waight, Ashley Caudell, Antonio Ladrón-de-Guevara, Michael J. Giannetto, Lauren M. Hablitz, Maiken Nedergaard
This study shows that α2-adrenergic agonist anesthesia increases glymphatic CSF influx, independent of tracer injection duration, compared to isoflurane.
bioRxiv · Jun 30, 2026 · PreprintNeuroscience