In situ structure of rotavirus VP1 RNA-dependent RNA polymerase
Simon Jenni, Eric N. Salgado, Tobias Herrmann, Zongli Li, Timothy Grant, Nikolaus Grigorieff, Stefano Trapani, Leandro F. Estrozi, Stephen C. Harrison
The paper determines the in situ structure of rotavirus VP1 RNA-dependent RNA polymerase using local reconstruction, showing conformational changes during transcription and stochastic distribution of VP1 molecules.
Journal of Molecular Biology · Jun 21, 2019Peer-reviewedMolecular Biology