Simon Jenni

This study uses cryogenic electron tomography to visualize the mechanism of membrane perforation during rhesus rotavirus entry, linking structural data with live-cell imaging.

The paper determines the cryo-EM structure of immature, small VLPs of dengue virus type 2, revealing octahedral symmetry and prM-E heterodimer clustering, with implications for vaccine design.

This study confirms that the rotavirus VP5*/VP8* conformational transition enables membrane permeabilization to Ca2+ through C-terminal segment insertion.

The paper determines the structure of infectious VSV particles using cryo-EM and computational classification, revealing the organization of the RNP and matrix proteins in the viral shaft and tip.

This paper presents the structure of the rabies virus polymerase complex determined by electron cryo-microscopy, revealing its pre-initiation conformation and differences from elongation states.

The paper reports the structure of vesicular stomatitis virus L protein in complex with its phosphoprotein cofactor, revealing how P induces a closed conformation for RNA synthesis.

The paper determines the in situ structure of rotavirus VP1 RNA-dependent RNA polymerase using local reconstruction, showing conformational changes during transcription and stochastic distribution of VP1 molecules.