Robust differentiation of human enteroendocrine cells from intestinal stem cells
Daniel Zeve, Eric Stas, Joshua de Sousa Casal, Prabhath Mannam, Wanshu Qi, Xiaolei Yin, Sarah Dubois, Manasvi S. Shah, Erin Phillips Syverson, Sophie Hafner, Jeffrey M. Karp, Diana L. Carlone, José Ordovás-Montañés, David T. Breault
This study develops a method to differentiate human intestinal stem cells into functional enteroendocrine cells using small molecule targeting of specific signaling pathways.
Nature Communications · Jan 11, 2022Peer-reviewedDevelopmental Biology