Machine-Guided Dual-Objective Protein Engineering for Deimmunization and Therapeutic Functions
Eric Wolfsberg, Jean-Sebastien Paul, Josh Tycko, Binbin Chen, Michael Cory Bassik, Lacramioara Bintu, Ash A. Alizadeh, Xiaojing J. Gao
The paper presents a workflow using machine learning to optimize protein function and reduce immunogenicity in cell and gene therapies.
Cell Systems · Feb 28, 2025Peer-reviewedBioengineering