Author

Eva Guchen

École Nationale Vétérinaire de Toulouse

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Anne LespineiD· 3 shared Élise CourtotiD· 2 shared Rémy BetousiD· 2 shared Albane le MaireiD· 1 shared Chérine BecharaiD· 1 shared Clara BlancfuneyiD· 1 shared Fabrice GuégnardiD· 1 shared Felipe Ramon‐PortugaliD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersGenomics

Anne LespineORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Sex-biased transcriptional rewiring of neuronal circuits associated with eprinomectin resistance in Haemonchus contortus

Rémy Betous, Robin Lioutaud, Julie Petermann, Sophie Jouffroy, Philippe Jacquiet, Eva Guchen, Élise Courtot, Léa Bordes, Fabrice Guégnard, Guillaume Sallé, Stephen R. Doyle, Anne Lespine

The paper identifies sex-biased transcriptional changes and genetic loci associated with eprinomectin resistance in Haemonchus contortus using genomic and transcriptomic analyses.

bioRxiv · Jul 23, 2026 · PreprintGenomics

Structural and evolutionary insights into DAF-12 interactions with transcriptional coactivators in parasitic nematodes

Manon Mallet, Yéléna Martin, João E. Carvalho, Eva Guchen, Rémy Betous, Chérine Bechara, Anne Lespine, Michael Schubert, William Bourguet, Albane le Maire

This study investigates DAF-12 interactions with transcriptional coactivators in parasitic nematodes using structural and bioinformatic approaches, revealing conserved and nematode-specific mechanisms of coactivator recruitment.

PLoS Pathogens · Jul 20, 2026Peer-reviewedBiochemistry

Critical Role of P-Glycoprotein-9 in Ivermectin Tolerance in Nematodes

Clara Blancfuney, Eva Guchen, Marie Garcia, Julien Faccini, Jean‐François Sutra, Felipe Ramon‐Portugal, Élise Courtot, Marlène Z. Lacroix, Roger K. Prichard, Anne Lespine, Mélanie Alberich

This study identifies P-glycoprotein-9 as a key mediator of ivermectin resistance in nematodes by showing its role in drug efflux and demonstrating functional conservation across species.

PLoS Pathogens · Mar 23, 2026Peer-reviewedMicrobiology