PTX3 Governs Fibroblast-Epithelial Dynamics in Lung Injury and Repair
Marie‐Therese Bammert, Ines Kollak, Jan Hoffmann, Eva Peter, Meshal Ansari, Holger Schlüter, Jun Li, Alexandre Rosa Campos, Coralie Viollet, Florian Gantner, Muriel Lizé, Matthew James Thomas, Huy Quang Le
This study identifies PTX3 as a key antifibrotic factor secreted by fibroblasts that modulates epithelial repair in acute injury and exacerbates damage in chronic injury.
Journal of Biological Chemistry · Jun 26, 2025Peer-reviewedMolecular Biology