ABHD2 activity is not required for the non-genomic action of progesterone on human sperm
Madison Edwards, Alexandra Amaral, Eve M. Carter, Oliver Arnolds, Karen Vester, Anna Thrun, Edvard Wigren, Evert Homan, P. Ribera, Kirsty Bentley, Martin Haraldsson, Nmesoma Theo-Emegano, Peter Loppnau, Magdalena M. Szewczyk, Michelle Ada Cao, , Claudia Tredup
This study shows that ABHD2 activity is not required for progesterone-induced Ca2+ influx via CatSper and subsequent motility changes in human sperm.
Human Reproduction · May 29, 2026Peer-reviewedCell Biology