Repeated Plasmodium vivax blood stage infection provides sterile protection against homologous challenge in non-human primates
N. Obaldia, J. L. da Silva Filho, M. Nunez, K. Glass, T. Oulton, F. Achcar, G. Wirjanata, M. Duraisingh, P. Felgner, K. Tetteh, Z. Bozdech, T. Otto, M. Marti
This study shows that repeated P. vivax infections in Aotus monkeys induce sterile immunity against homologous strain challenges but only partial protection against heterologous strains.
bioRxiv · Feb 13, 2023 · PreprintMicrobiology