Neutral sphingomyelinase 2 regulates inflammatory responses in monocytes/macrophages induced by TNF-α
F. Al-Rashed, Z. Ahmad, R. Thomas, M. Melhem, A. J. Snider, L. M. Obeid, F. Al-Mulla, Y. A. Hannun, R. Ahmad
This study shows that nSMase2 regulates TNF-α-induced inflammatory responses in monocytes/macrophages by affecting CD11c expression and inflammatory mediator secretion.
bioRxiv · May 6, 2020Immunology