Author

F. B. Larsen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein sequence· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Stein· 2 shared K. Lindorff-Larsen· 2 shared R. Hartmann-Petersen· 2 shared A. B. Abildgaard· 1 shared C. Andreasson· 1 shared C. Kampmeyer· 1 shared J. Dideriksen· 1 shared K. E. Johansson· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBiochemistry

A. Stein

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Rare catechol-O-methyltransferase (COMT) missense variants are structurally unstable proteasome targets

F. B. Larsen, M. Cagiada, J. Dideriksen, A. Stein, K. Lindorff-Larsen, R. Hartmann-Petersen

The paper shows two rare COMT missense variants are structurally unstable, leading to proteasomal degradation and reduced enzyme levels, with degradation independent of COMT isoform.

bioRxiv · Jan 3, 2023Biochemistry

HSP70-binding motifs function as protein quality control degrons

A. B. Abildgaard, V. Voutsinos, S. D. Petersen, F. B. Larsen, C. Kampmeyer, K. E. Johansson, A. Stein, T. Ravid, C. Andreasson, M. K. Jensen, K. Lindorff-Larsen, R. Hartmann-Petersen

The paper shows that Hsp70-binding motifs can function as PQC degrons, targeting misfolded proteins for degradation in yeast and human cells.

bioRxiv · Dec 22, 2021Biochemistry