Inhibition of myeloperoxidase prevents thoracic aortic aneurysm formation in Marfan mice
D. Mehrkens, F. S. Nettersheim, F. Ballmann, J. Bastigkeit, A. Brueckner, J. Dohr, S. Geissen, L. De Vore, P. Schelemei, F. R. Picard, M. Kochen, S. Braumann, W. Kreuzberg, A. Hof, H. Guthoff, , H. Winkels
This study shows that inhibiting myeloperoxidase prevents thoracic aortic aneurysms in Marfan mice by reducing inflammation and extracellular matrix damage.
bioRxiv · Nov 24, 2022 · PreprintImmunology