Anti-inflammatory properties of chemical probes in human whole blood: focus on prostaglandin E2 production
F. Bergqvist, Y. Sundström, M. Shang, I. Gunnarsson, I. Lundberg, M. Sundström, P.-J. Jakobsson, L. Berg
The paper screens chemical probes in human whole blood to assess their effect on PGE2 and IL-8 production, identifying MEK inhibitors as anti-inflammatory and JAK inhibitor as pro-inflammatory.
bioRxiv · Dec 30, 2019Immunology