Adjuvant effects of multifunctional transcription factor and BCG target YB-1: exogenous YB-1 enhances specific antibody production in vivo and protects mice against lethal E. coli challenge
A. O. Shepelyakovskaya, L. Alekseeva, E. A. Meshcheryoakova, K. Boziev, A. Tsitrina, V. Ivanov, F. Brovko, Y. Kotelevtsev, R. Lathe, A. G. Laman
This study shows that administering YB-1 enhances antibody production and protects mice from lethal E. coli infection, suggesting its potential as an adjuvant.
bioRxiv · Nov 9, 2022 · PreprintImmunology