The proto CpG island methylator phenotype of sessile serrated adenoma/polyps
H. R. Parker, S. Orjuela, A. Martinho Oliveira, F. Cereatti, M. Sauter, H. Heinrich, G. Tanzi, A. Weber, P. Komminoth, S. Vavricka, L. Albanese, F. Buffoli, M. D. Robinson, G. Marra
This paper identifies distinct DNA methylation patterns in sessile serrated adenomas/polyps (SSA/Ps) compared to conventional adenomas, introducing the term 'proto-CIMP' and highlighting their potential as biomarkers.
bioRxiv · Jun 27, 2018Cancer Biology