Specific genomic targeting of the RNF12/RLIM E3 ubiquitin ligase selectively programmes developmental transcription
C. Espejo-Serrano, C. Aitken, B. F. Tan, D. G. May, R. J. Chrisopulos, K. J. Roux, S. G. Mackintosh, J. Gribnau, F. Bustos, C. Gontan, G. M. Findlay
This study identifies how RNF12/RLIM E3 ubiquitin ligase targets specific genomic regions to regulate gene expression through chromatin interactions and autoinhibitory mechanisms.
bioRxiv · Jun 14, 2023 · PreprintCell Biology