A precision medicine approach uncovers a unique signature of neutrophils in patients with brushite kidney stones
M. S. Makki, S. Winfree, J. E. Lingeman, F. A. Witzmann, E. M. Worcester, A. Krambeck, F. Coe, A. P. Evan, S. Bledsoe, K. Bergsland, S. Khochare, D. Barwinska, J. C. Willliams, T. M. El-Achkar
This study identifies a unique neutrophil signature in brushite kidney stone formers through multi-omics analysis, linking increased neutrophil infiltration and NETosis to tissue scarring and inflammation.
bioRxiv · Nov 16, 2019Pathology