A native mass spectrometry-based assay for rapid assessment of the empty/full capsid ratio in AAV gene therapy products
L. Strasser, T. E. Morgan, F. Guapo, F. Fuessl, D. Forsey, I. Anderson, J. Bones
The paper introduces a native mass spectrometry assay to rapidly assess the empty/full capsid ratio in AAV gene therapy products, showing good correlation with traditional methods.
bioRxiv · Jul 6, 2021Biochemistry