EPI-589, a redox-active neuroprotectant, potently protects cultured cells from oxidative stress and alleviates symptomatic and pathological progression of motor neuron disease in the wobbler mouse
Y. Matsumoto, K. Sampei, T. Nashida, Y. Fujii, N. Tani, F. Ishibashi, M. Yamanaka, T. Ishiyama
This study shows EPI-589, a redox-active compound, protects cells from oxidative stress and delays motor neuron disease symptoms in wobbler mice.
bioRxiv · Mar 13, 2022 · PreprintPharmacology & Toxicology