BiochemistrybioRxiv
Stabilization of a Protein by a Single Halogen-Based Aromatic Amplifier
K. E. Hage, N. B. Phillips, Y.-S. Chen…·M. A. Weiss
This study demonstrates that halogenation of an aromatic ring in insulin stabilizes the protein and enhances its resistance to fibrillation and biological activity.
DOI 10.1002/pro.70064