USP22 overexpression fails to augment tumor formation in MMTV-ERBB2 mice but loss of function impacts MMTV promoter activity
X. Kuang, A. Salinger, F. J. Benavides, W. J. Muller, S. Y. Dent, E. Koutelou
This study shows USP22 overexpression does not enhance ERBB2-driven tumorigenesis in MMTV-NIC mice, but its loss reduces tumor burden and affects MMTV promoter activity.
bioRxiv · Sep 28, 2022Cancer Biology