Author

F. J. Kull

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

C. R. Midgett· 2 shared G. P. Munson· 1 shared J. L. Day· 1 shared K. M. Talbot· 1 shared M. Pellegrini· 1 shared R. A. Swindell· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

C. R. Midgett

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Structural analysis of the master regulator Rns reveals a small molecule inhibitor of enterotoxigenic Escherichia coli virulence

C. R. Midgett, K. M. Talbot, J. L. Day, G. P. Munson, F. J. Kull

This study identifies decanoic acid as a small molecule inhibitor of Rns, a key regulator of ETEC virulence, offering a new approach for drug design against ETEC infections.

bioRxiv · Oct 5, 2020 · PreprintBiochemistry

A disulfide constrains the ToxR periplasmic domain structure, altering its interactions with ToxS and bile-salts

C. R. Midgett, R. A. Swindell, M. Pellegrini, F. J. Kull

This study shows that a disulfide bond in ToxR's periplasmic domain increases its affinity for ToxS and bile-salts, stabilizing its structure and function.

bioRxiv · Feb 24, 2020Microbiology