Analysis of cholesterol export from endo-lysosomes by Niemann Pick C2 protein using combined fluorescence and X-ray microscopy
A. Dupont, F. Lund, M. L. V. Jensen, M. Szomek, G. K. Nielsen, C. W. Heegaard, P. Guttmann, S. Werner, J. McNally, G. Schneider, S. Kapishnikov, D. Wustner
This study uses fluorescence and X-ray microscopy to show NPC2 facilitates cholesterol export from endo-lysosomes, altering membrane trafficking and organelle structure.
bioRxiv · Nov 6, 2018 · PreprintCell Biology