Interferon-gamma and TNF-alpha synergistically enhance the immunomodulatory capacity of Endometrial-Derived Mesenchymal Stromal Cell secretomes by differential microRNA and extracellular vesicle release
M. d. l. A. de Pedro, F. Marinaro, E. Lopez, M. Pulido, F. M. Sanchez Margallo, V. Alvarez, J. G Casado
This study shows that IFN-gamma and TNF-alpha priming enhances endMSCs' immunomodulatory capacity through increased IDO1 release, altered surface markers, and miRNA secretion.
bioRxiv · Jun 10, 2021Cell Biology