Cell BiologybioRxiv
Interferon-gamma and TNF-alpha synergistically enhance the immunomodulatory capacity of Endometrial-Derived Mesenchymal Stromal Cell secretomes by differential microRNA and extracellular vesicle release
M. d. l. A. de Pedro, F. Marinaro, E. Lopez…·J. G Casado
This study shows that IFN-gamma and TNF-alpha priming enhances endMSCs' immunomodulatory capacity through increased IDO1 release, altered surface markers, and miRNA secretion.
DOI 10.3390/ijms222212177