PRMT1-mediated methylation of the Large Drosha Complex regulates microRNA biogenesis
T. Bonaldi, V. Spadotto, R. Giambruno, E. Massignani, M. Mihailovich, F. Patuzzo, F. Ghini, F. Nicassio
This study identifies PRMT1-mediated methylation of the Large Drosha Complex as critical for miRNA biogenesis by regulating pri-to-pre-miRNA processing.
bioRxiv · Nov 9, 2018 · PreprintCell Biology