Author

T. Bonaldi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:chromatin & epigenetic regulation· 3 Research Focus:gene regulatory network inference· 3 Assay:proteomics· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2

Frequent Co-Authors

R. Noberini· 3 shared E. Massignani· 2 shared A. C. Calabuig· 1 shared A. Cuomo· 1 shared A. Marino· 1 shared A. Rocca· 1 shared B. Bernardes de Jesus· 1 shared B. Bola· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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3 shared papersCell Biology

R. Noberini

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Metabolic and age-associated epigenetic barriers during direct reprogramming of mouse fibroblasts into induced cardiomyocytes

F. Santos, M. Correia, R. Dias, B. Bola, R. Noberini, R. S. Ferreira, P. Domingues, J. Teixeira, T. Bonaldi, P. J. Oliveira, B. Bernardes de Jesus, C. Bar, S. Nobrega-Pereira

This study identifies metabolic and age-related epigenetic barriers in converting mouse fibroblasts to induced cardiomyocytes, showing that metabolic modulation enhances reprogramming efficiency.

bioRxiv · Feb 28, 2024Cell Biology

The assembly of cancer-specific ribosomes by the lncRNA LISRR suppresses melanoma anti-tumour immunity

S. Cinque, Y. Verheyden, S. Adnane, A. Marino, V. Katopodi, E. Demesmaeker, Z. Knezevic, S. Hanache, R. Vendramin, A. Cuomo, J. Pozniak, A. C. Calabuig, S. Tabruyn, O. Bechter, M. F. Baietti, , E. Leucci

This study identifies LISRR, a cancer-specific lncRNA that assembles immunosuppressive ribosomes in melanoma, suppressing anti-tumour immunity and resistance to immune checkpoint blockade.

bioRxiv · Jan 6, 2023 · PreprintCancer Biology

The histone code of the fungal genus Aspergillus uncovered by evolutionary and proteomic analyses

X. Zhang, R. Noberini, T. Bonaldi, J. Collemare, M. F. Seidl

This study identifies conserved and divergent chromatin-modifying enzymes in Aspergillus species through evolutionary and proteomic analyses, revealing unique modifications and gene losses.

bioRxiv · Jan 28, 2022Evolutionary Biology

Unperturbed dormancy recording reveals stochastic awakening strategies in endocrine treated breast cancer cells

D. Rosano, E. Sofyali, H. Dheman, D. Ivanoiu, N. Slaven, s. p. Hong, A. Rocca, S. Bravacini, s. ravaioli, r. Noberini, T. Bonaldi, L. Magnani

This study investigates dormancy and awakening in endocrine-treated breast cancer cells, revealing stochastic awakening strategies and the role of epigenetic decay.

bioRxiv · Apr 21, 2021 · PreprintCancer Biology

Pharmacological inhibition of LSD1 triggers myeloid differentiation by targeting GSE1, a novel oncogene in AML

L. Nicosia, F. L. Boffo, E. Ceccacci, I. Pallavicini, F. Bedin, E. Massignani, R. Ravasio, S. Minucci, T. Bonaldi

This study shows that LSD1 inhibitors induce AML cell differentiation by reducing GSE1, a novel oncogene, through transcriptional activation of immune response genes.

bioRxiv · Feb 16, 2021 · PreprintCancer Biology

PRMT1-mediated methylation of the Large Drosha Complex regulates microRNA biogenesis

T. Bonaldi, V. Spadotto, R. Giambruno, E. Massignani, M. Mihailovich, F. Patuzzo, F. Ghini, F. Nicassio

This study identifies PRMT1-mediated methylation of the Large Drosha Complex as critical for miRNA biogenesis by regulating pri-to-pre-miRNA processing.

bioRxiv · Nov 9, 2018 · PreprintCell Biology