Unsupervised cellular phenotypic hierarchy enables spatial intratumor heterogeneity characterization, recurrence-associated microdomains discovery, and harnesses network biology from hyperplexed in-situ fluorescence images of colorectal carcinoma
S. Furman, A. Stern, S. Uttam, D. L. Taylor, F. Pullara, S. C. Chennubhotla
LEAPH identifies spatial microdomains and recurrence-associated signaling networks in colorectal carcinoma using hyperplexed fluorescence images.
bioRxiv · Oct 2, 2020 · PreprintCancer Biology