Targeting a shared neoepitope derived from non-canonical translation of c-MYC oncogene in cancer cells
S. Depil, E. Baulu, A. Bolon, E. Etchegaray, F. Raimundo, A. Merienne, J. Martin, J. Grandsire, T. Richard, L. Tonon, C. Dubois, Y. Estornes, R. Boulos, O. Tabone, P. Bonaventura, , J.-J. Diaz
The paper identifies a shared neoepitope from non-canonical c-MYC translation in cancer cells that activates T cells to kill tumors without harming normal cells.
bioRxiv · May 23, 2024 · PreprintImmunology