Can calmodulin bind to lipids of the cytosolic leaflet of plasma membranes?
F. Scollo, C. Tempra, H. Evci, M. Riopedre-Fernandez, A. Olzynska, M. Javanainen, A. Uday, M. Cebecauer, L. Cwiklik, H. Martinez-Seara, P. Jungwirth, P. Jurkiewicz, M. Hof
The paper investigates whether calmodulin binds to lipids in the cytosolic leaflet of plasma membranes and finds that CaM interacts with PS and PE, with calcium inducing conformational changes and affecting membrane charge and stability.
bioRxiv · Dec 12, 2023Biophysics