Is evolutionary conservation a useful predictor for cancer long noncoding RNAs? Insights from the Cancer lncRNA Census 3
A. Vancura, A. H. Gutierrez, T. Hennig, C. Pulido-Quetglas, F. Slack, R. Johnson, S. Haefliger
The paper examines the relationship between evolutionary conservation and the discovery year of cancer lncRNAs, finding an inverse correlation that suggests potential sampling bias and questions the utility of evolutionary metrics in prioritizing cancer lncRNAs.
bioRxiv · Sep 1, 2022 · PreprintCancer Biology