Author

F. Sottile

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Cell Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

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E. Pedone· 1 shared F. Aulicino· 1 shared F. Lluis· 1 shared L. Marucci· 1 shared M. P. Cosma· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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1 shared paperCell Biology

E. Pedone

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1 paper

Recent·Most cited

Canonical Wnt pathway controls mESCs self-renewal through inhibition of spontaneous differentiation via β-catenin/TCF/LEF functions

F. Aulicino, F. Sottile, E. Pedone, F. Lluis, L. Marucci, M. P. Cosma

This study shows that canonical Wnt signaling inhibits mESC differentiation by β-catenin/TCF/LEF functions, and that non-functional β-catenin isoforms can rescue self-renewal defects.

bioRxiv · Jun 16, 2019Cell Biology