Mutations that adapt SARS-CoV-2 to mustelid hosts do not increase fitness in the human airway.
J. Zhou, T. P. Peacock, J. C. Brown, D. H. Goldhill, A. M. E. Elrefaey, R. Penrice-Randal, V. M. Cowton, G. De Lorenzo, W. Furnon, W. T. Harvey, R. Kugathasan, R. Frise, L. Baillon, R. Lassauniere, N. Thakur, , W. S. Barclay
The paper identifies spike mutations that adapt SARS-CoV-2 to mustelid hosts and assesses their impact on human infectivity and antigenicity.
bioRxiv · Aug 20, 2021 · PreprintMicrobiology