Chaperone-Mediated Reflux of Secretory Proteins to the Cytosol During Endoplasmic Reticulum Stress
A. Igbaria, P. I. Merksamer, A. Trusina, F. Tilahun, J. R. Johnson, O. Brandman, N. J. Krogan, J. S. Weissman, F. R. Papa
The paper identifies a chaperone-mediated process that refuxes properly folded ER proteins to the cytosol during ER stress, functioning parallel to ERAD.
bioRxiv · Mar 12, 2019Cell Biology