Author

A. Igbaria

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 3

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Organism:mouse· 1 Organism:yeast· 1

Frequent Co-Authors

A. Gilad· 1 shared A. Mohtar· 1 shared A. Trusina· 1 shared D. Sicari· 1 shared D. Thomas· 1 shared E. Chevet· 1 shared F. R. Papa· 1 shared F. Tilahun· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCell Biology

A. Gilad

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3 papers

Recent·Most cited

Chaperone Complexes From The Endoplasmic Reticulum (ER) And The Cytosol Inhibit wt-p53 By Activation The ER To Cytosol Signaling.

S. Dabsan, G. Zur, A. Gilad, A. Igbaria

The paper identifies DNAJB12 and DNAJB14 as key regulators of ER to cytosol signaling (ERCYS) that inhibit wild-type p53 during ER stress by facilitating protein reflux.

eLife · Apr 9, 2025Peer-reviewedCell Biology

Reflux of Endoplasmic Reticulum proteins to the cytosol yields inactivation of tumor suppressors

D. Sicari, R. Pineau, P.-J. Le Reste, L. Negroni, S. Chat, A. Mohtar, D. Thomas, R. Gillet, T. Hupp, E. Chevet, A. Igbaria

The paper identifies a mechanism where ER proteins are refluxed to the cytosol, inactivating tumor suppressors like p53 in glioblastoma cells.

bioRxiv · Apr 13, 2020Cell Biology

Chaperone-Mediated Reflux of Secretory Proteins to the Cytosol During Endoplasmic Reticulum Stress

A. Igbaria, P. I. Merksamer, A. Trusina, F. Tilahun, J. R. Johnson, O. Brandman, N. J. Krogan, J. S. Weissman, F. R. Papa

The paper identifies a chaperone-mediated process that refuxes properly folded ER proteins to the cytosol during ER stress, functioning parallel to ERAD.

bioRxiv · Mar 12, 2019Cell Biology