Hypervariable-Locus Melting Typing (HLMT): a novel, fast and inexpensive sequencing-free approach to pathogen typing based on High Resolution Melting (HRM) analysis
M. Perini, A. Piazza, S. Panelli, S. Papaleo, A. Alvaro, F. Vailati, M. Corbella, F. Saluzzo, F. Gona, D. Castelli, C. Farina, P. Marone, D. M. Cirillo, A. Cavallero, G. V. Zuccotti, F. Comandatore
HLMT provides a fast, inexpensive, sequencing-free pathogen typing method using HRM analysis, comparable to PFGE, MLST, and WGS for detecting high-risk clones in hospitals.
bioRxiv · Jul 1, 2021 · PreprintMicrobiology