Author

M. Corbella

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:database / resource· 1 Organism:human· 1

Frequent Co-Authors

F. Comandatore· 3 shared P. Marone· 3 shared A. Cavallero· 2 shared C. Bandi· 2 shared C. Farina· 2 shared C. Merla· 2 shared C. Rodrigues· 2 shared D. M. Cirillo· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersMicrobiology

F. Comandatore

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Catalytic Redundancies and Conformational Plasticity Drives Selectivity and Promiscuity in Quorum Quenching Lactonases

M. Corbella, J. Bravo, A. O. Demkiv, A. R. Calixto, K. Sompiyachoke, C. Bergonzi, M. H. Elias, S. C. L. Kamerlin

This study investigates the catalytic mechanisms and substrate specificity of the lactonase GcL, revealing its promiscuity in reaction mechanisms and broad substrate acceptance.

bioRxiv · May 1, 2024Biochemistry

Genetic barriers more than ecological adaptations shaped Serratia marcescens diversity

L. Sterzi, R. Nodari, F. Di Marco, M. L. Ferrando, F. Saluzzo, A. Spitaleri, H. Allahverdi, S. Papaleo, S. Panelli, S. G. Rimoldi, G. Batisti Biffignandi, M. Corbella, A. Cavallero, P. Prati, C. Farina, , F. Comandatore

This study shows genetic isolation, particularly through R-M systems, shaped Serratia marcescens diversity more than ecological adaptations.

bioRxiv · Jul 14, 2023 · PreprintEvolutionary Biology

One Health or Three? Transmission modelling of Klebsiella isolates reveals ecological barriers to transmission between humans, animals and the environment

H. A. Thorpe, R. Booton, T. Kallonen, M. J. Gibbon, N. Couto, V. A. Passet, J. Fernandez, C. Rodrigues, L. Matthews, S. Mitchell, R. Reeve, S. David, C. Merla, M. Corbella, C. Ferrari, , E. J. Feil

This study models Klebsiella transmission across human, animal, and environmental sources, finding limited AMR spread outside clinical settings and human-to-human transmission dominance.

bioRxiv · Aug 5, 2021 · PreprintMicrobiology

Hypervariable-Locus Melting Typing (HLMT): a novel, fast and inexpensive sequencing-free approach to pathogen typing based on High Resolution Melting (HRM) analysis

M. Perini, A. Piazza, S. Panelli, S. Papaleo, A. Alvaro, F. Vailati, M. Corbella, F. Saluzzo, F. Gona, D. Castelli, C. Farina, P. Marone, D. M. Cirillo, A. Cavallero, G. V. Zuccotti, F. Comandatore

HLMT provides a fast, inexpensive, sequencing-free pathogen typing method using HRM analysis, comparable to PFGE, MLST, and WGS for detecting high-risk clones in hospitals.

bioRxiv · Jul 1, 2021 · PreprintMicrobiology

Description of Klebsiella spallanzanii sp. nov. and of Klebsiella pasteurii sp. nov.

C. Merla, C. Rodrigues, V. Passet, M. Corbella, H. A. Thorpe, T. V. S. Kallonen, Z. Zong, P. Marone, C. Bandi, D. Sassera, J. Corander, E. J. Feil, S. Brisse

This paper describes two new Klebsiella species, K. spallanzanii and K. pasteurii, based on genomic and biochemical analyses of phylogroups Ko3 and Ko4, with type strains isolated from various sources.

bioRxiv · Jul 16, 2019Microbiology