ImmunologybioRxiv
Targeting HIV Env immunogens to B cell follicles in non-human primates through immune complex or protein nanoparticle formulations
J. T. Martin, C. T. Cottrell, A. Antanasijevic…·D. J. Irvine
This study shows that HIV Env immunogens can be concentrated in B cell follicles using immune complexes or protein nanoparticles, enhancing their localization in lymph nodes and potentially improving immune responses.
DOI 10.1038/s41541-020-00223-1